Tff1 cre

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August undefined, 2024

Web1 Oct 2024 · A gastric epithelium-specific CreERT2 mouse allele using the Anxa10 gene promoter (Anxa10-CreERT2) 29 , which is transcriptionally active throughout the stomach, showed tamoxifen-induced Cre... WebTFF1, a gastric tumor suppressor, is a single trefoil peptide originally detected in breast cancer cell lines but expressed mainly in the stomach; TFF2, a candidate of gastric cancer suppressor with two trefoil domains, is abundant in the stomach and duodenal Brunner's glands; and TFF3 is another single trefoil peptide expressed throughout the intestine …

Mouse Models of Human Gastric Cancer Subtypes With

Web1 Nov 2024 · Furthermore, the use of Tff1-Cre to delete Cdh1 resulted in columnar epithelial loss and replacement with squamous epithelium [214]. More recently with the elucidation of the molecular subtypes of human gastric cancer, genetic mouse models have been designed to recapitulate the molecular characteristics of the human disease rather than … WebCN111676243B CN202410386214.2A CN202410386214A CN111676243B CN 111676243 B CN111676243 B CN 111676243B CN 202410386214 A CN202410386214 A CN 202410386214A CN 111676243 B CN111676243 B CN 111676243B Authority CN China Prior art keywords cre sequence mouse gene epithelial cells Prior art date 2024-05-09 … phi stand for health

Glucocorticoids and Androgens Protect From Gastric

Web4 Feb 2024 · Europe PMC is an archive of life sciences journal literature. http://www.informatics.jax.org/allele/MGI:5633852 Web1 Dec 2024 · Cre/loxP System Carcinogenesis Targeted Therapy Abbreviations used in this paper 5-FU 5-fluoruracil CIN chromosomal instability EGF epidermal growth factor EGFR … phi stands for **

Three types of metaplasia model through Kras activation

Web1 Feb 2024 · In the stomachs of Tff1‐Cre;LSL‐KrasG12D mice, proliferating cell clusters expanded throughout the corpus glands, with foveolar cell expansion with ectopic Alcian blue‐positive mucins, oxyntic... Web16 Sep 2024 · Trefoil factor family (TFF) peptides mainly consist of characteristic TFF domains, which contain about 40 amino acid residues, including 6 conserved cysteine … phi stands for medical termWeb图 1 Tff1 CreERT2/+; Rosa26 tdTomato/+ 小鼠胃粘膜上皮细胞中tdTomato的表达情况。经Tamoxifen诱导后，Tff1 CreERT2/+; Rosa26 tdTomato/+ 双转基因鼠，可在小鼠胃粘膜上皮细胞中表达tdTomato。证明Tff1-(CreERT2)小鼠可以成为实现Tff1阳性细胞特异性敲除或表达 … phi stands for in hipaa

"Web27 Nov 2024 · A model is presented explaining the role of the lectin TFF1 as an antral tumor suppressor possibly regulating Lgr5+ antral stem cells in a paracrine or maybe autocrine fashion, with neighboring antral gland cells having a role as niche cells. PDF Loss of Pancreatic E-Cadherin Causes Pancreatitis-Like Changes and Contributes to Carcinogenesis " - Tff1 cre

Tff1 cre

(PDF) Mouse Models of Human Gastric Cancer Subtypes With …

WebExpression of TFF1 protein was checked in 52 paraffin-embedded tissues of BCs by immunochemistry, and serum concentration of TFF1 in 70 BC patients and 32 healthy … WebCorpus-derived organoids from Tff1-Cre;LSL-Kras G12D mice exhibited accelerated growth and abnormal differentiation with a loss of chief and parietal cell markers. Tff1-Cre;Pten …

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WebTamoxifen诱导Cre-ERT2小鼠使用指南. Cre-ERT2在无Tamoxifen诱导的情况下，在细胞质内处于无活性状态；当Tamoxifen诱导后，Tamoxifen的代谢产物4-OHT（雌激素类似物） … WebAlthough transgenic mice expressing the Cre recombinase in the gastric epithelium have been reported, there is a lack of models that allow inducible and reversible gene …

Web图 1 Tff1 CreERT2/+; Rosa26 tdTomato/+ 小鼠胃粘膜上皮细胞中tdTomato的表达情况。. 经Tamoxifen诱导后，Tff1 CreERT2/+; Rosa26 tdTomato/+ 双转基因鼠，可在小鼠胃粘膜 …

WebTamoxifen诱导Cre-ERT2小鼠使用指南. Cre-ERT2在无Tamoxifen诱导的情况下，在细胞质内处于无活性状态；当Tamoxifen诱导后，Tamoxifen的代谢产物4-OHT（雌激素类似物）与ERT结合，可使Cre-ERT2进核发挥Cre重组酶活性。. 查看. 【小鼠大学问】基因工程小鼠的命名规则. 常见的 ... http://www.cancerindex.org/geneweb/TFF1.htm

WebKras activation in pit cells and progenitor cells predominantly through Tff1-Cre drivers led to the development of gastric atrophy and foveolar hyperplasia 87. Interestingly, Kras G12D expression ...

Web活体. NM-KI-18039. Cdkn2a-Luc-2A-tdTomato-2A-CreERT2. 其他. 衰老细胞；肿瘤细胞. 活体. * 列表中存在部分Dre工具鼠，需要与Frox（Flanked by Rox sites，目的基因或序列被Rox位 … phi starsWeb31 Jan 2024 · Tg (Tff1-cre/ERT2,Tff2-rtTA,Tff3-luc)#Ern Transgene Detail MGI Mouse (MGI:5911344) Search All Search Tools Genes Genes & Markers Query Batch Query … tss bom fimWebCirc-TFF1 is a facilitator in breast cancer relying on TFF1 by absorbing miR-326, providing a novel promising target for BC treatment. Results revealed that the mRNA level of TFF1 in the colorectal cancer (CRC) tissues was significantly higher than … phi stand for healthcareWeb27 Nov 2024 · Europe PMC is an archive of life sciences journal literature. tss bookWeb21 Mar 2024 · TFF1 (Trefoil Factor 1) is a Protein Coding gene. Diseases associated with TFF1 include Gastric Ulcer and Bile Reflux . Among its related pathways are ESR-mediated … tss book interior design pdfWebTff1-Cre;Ptenflox/flox mice displayed similar changes to those seen in Tff1-Cre;LSL-KrasG12D mice, both with aberrant ERK activation within 3 months. In contrast, Tff1-Cre;Cdh1flox/flox mice initially showed signet ring-like cells that were rapidly lost with disruption of the mucosal surface, and later developed gastric epithelial shedding with … phi star of genesisWeb10 Jul 2024 · TFF1 contains a trefoil domain that is defined as a sequence of 38 or 39 amino acid residues containing six cysteine residues which are disulfide-linked 13. TFF1 plays a critical role in... phistaskcalendar