WebBiomolecular condensation partitions cellular contents and has important roles in stress responses, maintaining homeostasis, development and disease. Many nuclear and cytoplasmic condensates are rich in RNA and RNA-binding proteins (RBPs), which undergo liquid-liquid phase separation (LLPS). WebSep 3, 2024 · NPR1 Accumulates in the Cytoplasm and Undergoes SA-Triggered Condensate Formation To determine the likely cellular compartment where NPR1-mediated ubiquitination occurs, we analyzed the subcellular accumulation of the endogenous NPR1 after SA treatment.
Tuning the rheostat of immune gene translation
WebSep 26, 2024 · When expressed in a human osteosarcoma U2OS cell line, PopZ formed micron-sized cytoplasmic condensates (Fig. 2b) that underwent spontaneous fusion events (Fig. 2c) and displayed dynamic internal... Web12 hours ago · Bimolecular condensates are essentially non-membranous structures made up of spatially concentrated biomolecules [3].This basic principle of biophysics has attracted the attention of plant researchers in recent years and has shed light on the roles of bimolecular condensates in regulating crucial signaling pathways in plants [4].Growing … seho systems china ltd
Biomolecular condensates and cancer - PMC - National Center for ...
WebApr 7, 2024 · Condensates are formed during both the early and late viral cycle phases to create microenvironments to facilitate and optimize viral replication and likely, to shield the viral genome from anti-viral innate immune host responses (Fig. 1).Often, condensates serve to organize cellular biochemistry by bringing the correct partners together in a … WebDec 18, 2024 · Eukaryotic cytoplasm organizes itself via both membrane-bound organelles and membrane-less biomolecular condensates (BMCs). Known BMCs exhibit liquid-like … WebDec 14, 2024 · Fig. 1: Plant miRNA processing occurs in liquid–liquid phase-separated condensates. Pre-miRNA is bound by DCL1, SE, and HYL1. Intrinsically disordered regions (IDRs) of SE promote liquid–liquid... sehprofil